北京师范大学化学学院
     
 

发布时间: 2015-12-31  浏览次数:

崔孟超

崔孟超 English

 

副教授,博士生导师,理学博士(北京师范大学),联合培养博士(京都大学)

通信地址:北京市新街口外大街19号 北京师范大学化学学院

邮编:100875

电话:010 5880 8891

传真:010 5880 8891

电子邮箱:cmc@bnu.edu.cn

课题组主页:https://www.x-mol.com/groups/Cui_Mengchao

 

讲授课程

放射性药物化学基础,放射性药物化学实验,无机与分析化学实验

研究兴趣

放射性药物化学、分子影像学

主持项目

  1. 国家自然科学基金面上项目(批准号:21571022)
  2. 国家重大新药创制子课题(批准号:2014ZX09507007-002)
  3. 国家自然科学基金青年项目(批准号:21201019)
  4. 北京市自然科学基金预探索项目(批准号:7143180)

获奖信息

  1. 2014年度肖伦青年科技奖
  2. 2012年北京市优秀博士论文

代表性论文

 
  1. Hualong Fu, Peiyu Tu, Liu Zhao, Jiapei Dai, Boli Liu, Mengchao Cui*. Amyloid-β Deposits Target Efficient Near-Infrared Fluorescent Probes: Synthesis, in Vitro Evaluation and in Vivo Imaging. Anal. Chem. 2016, 88: 1944-1950.
  2. Hualong Fu, Mengchao Cui*, Liu Zhao, Peiyu Tu, Kaixiang Zhou, Jiapei Dai, Boli Liu. Highly Sensitive Near-Infrared Fluorophores for in Vivo Detection of Amyloid-beta Plaques in Alzheimer's Disease. J. Med. Chem. 2015, 58: 6972-6983.
  3. Kaixiang Zhou, Hualong Fu, Liang Feng, Mengchao Cui*, Jiapei Dai, Boli Liu. The synthesis and evaluation of near-infrared probes with barbituric acid acceptors for in vivo detection of amyloid plaques. Chem. Commun. 2015, 51: 11665-11668.
  4. Hualong Fu, Mengchao Cui*, Peiyu Tu. et al. Evaluation of molecules based on the electron donor-acceptor architecture as near-infrared β-amyloidal-targeting probes. Chem. Commun. 2014, 50: 11875-11878
  5. Yanping Yang, Mengchao Cui*, Xiaoyang Zhang. et al. Radioiodinated benzyloxybenzene derivatives: a class of flexible ligands target to β-amyloid plaques in Alzheimer's brains. J. Med. Chem. 2014, 57: 6030-6042.
  6. Mengchao Cui, Masahiro Ono, Hiroyuki Watanabe. et al. Smart Near-Infrared Fluorescence Probes with Donor-Acceptor Structure for in Vivo Detection of β-Amyloid Deposits. J. Am. Chem. Soc. 2014, 136: 3388-3394.
  7. Zijing Li, Mengchao Cui*, Jiapei Dai. et al. Novel Cyclopentadienyl Tricarbonyl Complexes of 99mTc mimicking Chalcone as Potential Single-Photon Emission Computed Tomography Imaging Probes for β-Amyloid Plaques in Brain. J. Med. Chem. 2013, 56: 471-482.
  8. Mengchao Cui*, Xuedan Wang, Pingrong Yu. et al. Synthesis and Evaluation of Novel 18F Labeled 2-Pyridinylbenzoxazole and 2-Pyridinylbenzothiazole Derivatives as Ligands for Positron Emission Tomography (PET) Imaging of β-Amyloid Plaques. J. Med. Chem. 2012, 55: 9283-9296. (Cover Article)
  9. Mengchao Cui, Masahiro Ono, Hiroyuki Kimura. et al. Novel 18F-Labeled Benzoxazole Derivatives as Potential Positron Emission Tomography Probes for Imaging of Cerebral β-Amyloid Plaques in Alzheimer’s Disease. J. Med. Chem. 2012, 55: 9136-9145.
  10. Mengchao Cui, Masahiro Ono, Hiroyuki Kimura. et al. Synthesis and Structure-Affinity Relationships of Novel dibenzylideneacetone Derivatives as Probes for Human Beta-Amyloid Plaques. J. Med. Chem. 2011, 54: 2225-2240.

 
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