通信地址：北京市海淀区新街口外大街19号 北京师范大学化学学院

邮编：100875

电子邮箱：zhulin@bnu.edu.cn

讲授课程

本科生“综合实验—PET药物自动化合成”，硕士研究生“放射性药物进展”，博士研究生“现代化学研究方法学—放射性药物新药研发思路”

研究兴趣

中枢神经系统受体显像分子探针、肿瘤靶向放射性药物、放射性药物化学、新型放射性药物临床转化。

代表性论文

1. Zhu, Lin, et al. “Expanding the scope of fluorine tags for PET imaging.” Science, 2013, 342(6157): 429-430

2. Zhu, Lin, et al. “PET/SPECT imaging agents for neurodegenerative diseases.” Chemical Society Reviews, 2014, 43(19): 6683-6691.

3. Zhu, Lin, et al. "Metabolic imaging of glutamine in cancer." Journal of Nuclear Medicine 58.4 (2017): 533-537.

4. Li, Linlin, et al. "⁶⁸Ga-labelled-exendin-4: New GLP1R targeting agents for imaging pancreatic β-cell and insulinoma." Nuclear Medicine and Biology 102 (2021): 87-96.

5. Luo, Yang, et al. "Development of [⁶⁸Ga] Ga/[¹⁷⁷Lu] Lu-DOTA-NI-FAPI-04 containing a nitroimidazole moiety as new FAPI radiotracers with improved tumor uptake and retention." Journal of Medicinal Chemistry 68.1 (2024): 348-360.

6. Wang, Ran, et al. "Novel [⁶⁸Ga/¹⁷⁷Lu] Ga/Lu-AZ-093 as PSMA-targeting agent for diagnosis and radiotherapy." Molecular Pharmaceutics 21.7 (2024): 3256-3267.

7. Li, Linlin, et al. "Comparison of novel PSMA-targeting [¹⁷⁷Lu] Lu-P17-087 with its albumin binding derivative [¹⁷⁷Lu] Lu-P17-088 in metastatic castration-resistant prostate cancer patients: a first-in-human study." European Journal of Nuclear Medicine and Molecular Imaging 51.9 (2024): 2794-2805.

8. Li, Anqi, et al. "[¹⁸F]-D3FSP β-amyloid PET imaging in older adults and alzheimer’s disease." European Journal of Nuclear Medicine and Molecular Imaging 51.13 (2024): 3990-4000.

9. Zhao, Ruiyue, et al. "First-in-human study of D6-[¹⁸F] FP-(+)-DTBZ, a novel VMAT2 tracer: whole-body biodistribution and brain PET comparison with [¹⁸F] FP-(+)-DTBZ (AV-133)." EJNMMI Radiopharmacy and Chemistry 9 (2024): 71.

10. Jin, Wenbin, et al. "PSMA and SSTR2 Dual-Targeting Theranostic Agents for Neuroendocrine-Differentiated Prostate Cancer (NEPC)." Journal of Medicinal Chemistry 68.2 (2025): 1984-1993.