|
刘红云 |
副教授，博士生导师，理学博士 通信地址：北京市海淀区新街口外大街19号化学楼 邮编：100875 电话：010 58807843； 传真：010 58802075 电子邮箱：liuhongyun@bnu.edu.cn |
招生信息
代码：070302
专业：分析化学
方向：生物电分析化学与生物传感
简历
2008.7-至今 |
北京师范大学化学学院 |
副教授 |
|
2008.9-2010.9 |
University of Connecticut (美国) |
Visiting Research Assistant Professor |
|
2005.8 – 2008.7 |
北京师范大学化学学院 |
讲师 |
|
2000.9 - 2005.7 |
北京师范大学化学系 |
获理学博士学位 |
|
1996.9 - 2000.7 |
北京师范大学化学系 |
获理学学士学位 |
研究兴趣
智能筛选治疗退行性神经疾病的小分子药物
生物分子逻辑门与生物计算
电化学生物传感器
承担科研项目情况
智能筛查基于金属离子诱导Ab聚集的抗阿尔兹海默症潜在药物，宁夏回族自治区科技厅重点研发计划项目（东西部合作项目），骨干
新型固相电化学发光分子印迹阵列传感器用于高灵敏分析食品中抗生素残留的研究，北京市自然基金，主持
新型高通量电化学发光分子印迹生物传感技术用于灵敏筛查动物源食品中抗生素残留，宁夏回族自治区科技厅重点研发计划项目（东西部合作项目），骨干
基于Ru-纳米粒子复合物的电致化学发光检测碳纳米管的生物降解产物对DNA的损伤，国家自然基金，主持
基于层层组装薄膜开关性质的生物电催化与生物传感，教育部高等学校博士点研究基金，主持
代表性论文
1. Shi, J.; Zhu, W.; Yan, J.; Xiao, C., Yao, H.; Meng, L.; Liu Hongyun*; Mao, L.* Machine Learning-Assisted Screening of Small-Molecule Drugs in Protein Aggregation and ROS Generation Based on ECL and CV Dual-Mode Signals Amplified by DNA,Chem. Sci. 2026, Accepted.
2. Wang, Y.#; Lv, M.#; Zhu, W.; Yan, J.; Shi, J.; Qin, Z.; Zhang, X.; Yao, H.; Meng, L.; Liu Hongyun*; Mao, L.* Study of the Aggregation Behavior of Proteins Related to Neurodegenerative Diseases Based on the Photoluminescence of Perovskite Nanocrystals, Anal. Chem. 2025, 97, 27805−27814.
3. Xiao, C.#; Shi, J.#; Yan, J.; Xiao, R.; Wang, Y.; Yao, H.; Meng, L.; Liu Hongyun*; Mao, L.* Intelligent Screening of Functional Small Molecules for Targeting Metal-Induced Protein Aggregation, Anal. Chem.2025, 97, 10328−10336.
4. Wang, Y.; Shi, J.; Xiao, R.; Xiao, C.; Yao, H.*; Meng, L.*; Liu Hongyun* Dual-Optical Signal Molecular Logic System Based on CsPbBr3@SiO2 Film Electrodes with Modulated Photoluminescence and Electrochemiluminescence Behaviors, J. Phys. Chem. C2023, 127, 20919−20928.
5. Li, J.; Shi, J.; Wang, Y.; Yao, H.*; Meng, L.*; Liu Hongyun*, An Elaborate Biomolecular Keypad Lock Based on Electrochromism of Viologen Derivatives and Bioelectrocatalytic Reduction of CO2 at Supramolecular Hydrogel Film Electrodes, Biosens. Bioelectron., 2023, 238, 115560.
6. Xiao, R.; Wei, W.; Li, J.; Xiao, C.; Yao, H.; Liu Hongyun*, Constructing Combinational and Sequential Logic Devices Through an Intelligent Electrocatalytic Interface with Immobilized MoS2 Quantum Dots and Enzymes, Talanta, 2022, 248, 123615.
7. Wei, W.; Li, J., Yao, H.; Liu Hongyun*, A Molecular Keypad Lock with 3-Output Signals Built on Stimulus-Responsive Polymer Film Electrodes Containing Diallyl Viologen, Electrochim. Acta, 2022, 406, 139839.
8. Li, J.; Xiao, C.; Wei, W.; Xiao, R.; Yao, H.; Liu Hongyun*, Constructing a Facile Biocomputing Platform Based on Smart Supramolecular Hydrogel Film Electrodes with Immobilized Enzymes and Gold Nanoclusters, ACS Appl. Mater. Interfaces, 2021, 13, 36632−36643.
9. Wei, W.; Li, J.; Yao, H.; Shi, K.; Liu Hongyun*, A Versatile Molecular Logic System based on Eu(III) Coordination Polymer Film Electrodes Combined with Multiple Properties of NADH,Phys. Chem. Chem. Phys., 2020, 22, 22746-22757.
10. 肖聪, 廉文静, 姚惠琴, 杨宝华, 刘红云*, 基于信号放大策略的分子印迹-电化学发光抗生素传感器研究进展, 分析化学，2022, 50 (2), 173−182.